CA24124 - Network for the Advancement of Neutropenia Research and Patient Support (Neutro-NARPS)

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Neutro-NARPS:
From Bench to Bedside

 

KRAKOW
03-05 September
2026
 
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COST ACTION NEUTRO NARPS: From Bench to Bedside

1st YOUNG RESEARCHERS WORKSHOP/MEETING &

2nd WORKING GROUPS MEETING

joint with

THE 34th LOCAL LIAISON PHYSICIAN MEETING OF THE EUROPEAN BRANCH OF THE

 SEVERE CHRONIC NEUTROPENIA INTERNATIONAL REGISTRY (SCNIR)

KRAKOW, 03-05 September, 2026

Host: Prof Joanna Cichy and the Dept. of Immunology

Faculty of Biochemistry, Biophysics and Biotechnology (FBBB),
the Jagiellonian University, Krakow, Poland

Venue: Audytorium Maximum, Krupnicza 33 St.,

AGENDA outline (time zone local, CEST)

Download the Agenda (PDF)

DAY 1
YOUNG RESEARCHERS (YR) WORKSHOP

08:30 – 09:00Registration
09:00 – 10:00Introductory Sessions
  • Welcome (H. Papadaki, C. Dufour, J. Cichy)
  • Welcome and Presentation of Young NEUTRO-NARPS Group, Ice-breakers (V. Kargas, A. Skakic)
10:00 – 12:302 Sub-groups of YR sessions
Separate pre-defined groups of ECIs will try to work on preselected questions/queries on Chronic Neutropenias under the supervision of facilitators/tutors. Their findings and proposals will be presented and discussed on the third day of the Meeting.
(pre-registration will be needed among invited participants)                             

General moderators: V. Kargas, A. Skakic

Group 1: Congenital Neutropenia: a case based workshop focused on patient diagnosis,follow-up, novel and experimental therapies (e.g. CRISPR/gene therapy, iPS, etc)
Tutors: J. Skrzeczynska-Moncznik, A.-S. Hellmuth

Group 2: ACKR1/DARC-associated neutropenia (ADAN): a case based workshop focused on the diagnosis, follow-up, clinical significance, known data and unknown parameters of mechanisms leading to low ANC
Tutors: I. Pelagiadis, K. Pavlaki

12:30 – 14:00Lunch Break
14:00 – 16:00

Meet-the-Expert Sessions (Chairs: H. Papadaki, J. Cichy, C. Dufour)

  • Erythroid ACKR1 Deficiency: From Genetic Loss to Downstream Effects and Their Mechanisms” (A. Rot)
  • How to establish a Neutropenia Clinic in 2026 (C. Dufour)
  • Microbiome–Inflammation–Neutrophil Axis in Acquired Chronic Neutropenia (I. Lagkouvardos)
  • What does your blood remember? The memory of hematopoietic stem cells”  (K. Szade)
16:00 – 16:30Coffee Break
16:30 – 18:00Time allocated to Young Researchers for preparation of the presentation on Day 3

Networking dinner
 

DAY 2
WORKING GROUPS MEETING

 

07:30 – 08:00Registration
08:00 – 09:00

WG-1 Session
(Leaders: A. Warren, K. Welte, I. Touw, M. Bartels)

  • The role of ribosomal state in cell fate decisions and disease phenotypes (A. Warren)
  • Role of inflammation in clonal hematopoiesis in congenital neutropenias (J. Skokowa)
  • Clonal hematopoiesis in congenital neutropenias and Shwachman-Diamond-Syndrome (M. Klimiankou)
  • The evolving spectrum of congenital neutropenia syndromes: watch to learn (M. Bartels)
09:00 – 10:00

WG-2 Session
(Leaders: F. Fioredda, A. Eliopoulos, G. Tsaknakis)

  • Last findings and next steps on Non-Remitting Neutropenia in children & Chronic Idiopathic Neutropenia in adults (F. Fioredda)
  • Clinical Data Insights From Cypriot Neutropenic Patients (Κ. Pavlaki, P. Papasavva)
  • Beyond Race: Can Duffy Phenotype Occur Across Diagnoses and Relate to Blood Counts in Chronic Neutropenia? (R. Cerqueira)
  • Exploring the Diet–Inflammation Axis in Chronic Neutropenia (A. Eliopoulos)
10:00 – 10:30Coffee break
10:30 – 11:30

WG-3 Session
(Leaders: H. Latsoudis, G. Cavalca)

  • Demo on the Neutro_NARPS Information Management System Prototype (N. Angeli, V. Tzikoulis)
  • Significance of the data sharing and integration for the IMS development and Chronic Neutropenia risk factor profiling. (H. Latsoudis, G.  Manikis)
11:30 – 12:30

WG-4 Session
(Leaders: C. Simoglou Karali, M. Spanoudakis, A. Pierini)

  • Multimodal Evaluation of Drug-Induced Neutropenia: Integration of Haematologic, Genomic, and Cytometry-Based Profiling (C. Simoglou Karali)
  • Teaching AI the Regulatory Code: From DNA sequence to cell type Towards applications in neutropenia (S. Riva)
12:30 – 13:30Lunch break
13:30 – 14:30

WG-5 Session
(Leaders: J. Skokowa, J. Cichy, V. Bezzerri)

  • New therapeutic opportunities for severe congenital neutropenia (J. Skokowa)
  • Serine Proteases and Their Regulators in iPSC-Based Studies of Neutropenia (J. Cichy)
  • Update on Translational Readthrough-Inducing Drug Development in Inherited Bone Marrow Failure Syndromes (A. M. Hristodor)
14:30 – 15:30

WG-6 Session
(Leaders: C. Zeidler, C. Karamanidou, E. Laane)

  • Quality of Life assessment (S. Salek)
  • Update on the literature search (C. Karamanidou)
  • Suggestions for a QoL assessment for patients with chronic neutropenia (C. Zeidler)
  • Progress in the EHA SWG on QoL and possible interaction with the Neutro-NARPS (E. Laane)

Guided Tour
Networking dinner

 

DAY 3
PARALLEL SESSIONS
YOUNG RESEARCHERS (YR) MEETING
08:00 – 09:00

Oral presentations of abstracts
(Chairs: M. Klimiankou, J. Skrzeczyńska, O. Steinberg-Shemer)

  • PROTAC-mediated Degradation of Neutrophil Elastase Reveals ERAD Activation in ELANE-related Neutropenia (V. Makaryan)
  • Modeling ELANE-Associated Congenital Neutropenia Using iPSC Lines with Modified Elafin Expression (K. Gajewski)
  • Neutropenia-associated alterations in adipose tissue remodeling during psoriatic skin inflammation (I. Sinkevich)
  • Genetic Landscape of Congenital Neutropenia and Neutropenia-Associated Bone Marrow Failure Syndromes in the Polish Slavic Cohort (G. Chabrzyk)
  • Descriptor-Guided Explainable QSAR Model for Predicting Drug-Induced Neutropenia Risk and Supporting Toxicity-Aware Molecular Optimization (G. Karaduman)
09:00 – 10:30Poster Walk
Moderators: (V. Tomacinschii, A. Mazur, R. Cerqueira)
10:30 – 10:45Coffee break
10:45 – 11:45Presentations of Young sub-groups from Day 1
(Chairs: A. Skakic, V. Kargas)
11:45 – 12:15JOINT EHA & NEUTRO-NARPS Session
(Chairs: H. Papadaki, C. Dufour)
The EHA/Neutro-NARPS interaction (V. Lotushko)
12:15 – 13:45

Neutro-NARPS Partners and Industry session
(Chairs: H. Papadaki, C. Dufour, J.Cichy)

  • RARE Diseases ORG Greece (K. Theochari)
  • Results of survey of Diversity/Inclusion/Equality Team (A. Catic-Djordjevic)
  • Seeing More, Discovering More: An Introduction to Full Spectrum Profiling (E. Swart)
  • The Ongoing Development of Mavorixafor in the Treatment of WHIM Syndrome and Chronic Neutropenia (K. Adell)
13:45 – 14:45Lunch break

PARALLEL SESSIONS:

LOCAL LIAISON PHYSICIANS (LLP) MEETING OF THE EUROPEAN BRANCH OF THE SEVERE CHRONIC NEUTROPENIA INTERNATIONAL REGISTRY (SCNIR)

09:30 – 19:00LLP – SCNIR Meeting
Download the agenda (PDF)
SPEAKER/ WG-LEADER/ TUTOR *INSTITUTION of AFFILIATIONCOUNTRY of AFFILIATION
DrKatrinaAdellMedical Director, Clinical Development, X4 Pharmaceuticals Inc, Boston MAUSA
MsNataliaAngeliSchool of Medicine, University of CreteGreece
DrMarijeBartelsDepartment of Pediatric Hematology, University Medical Center Utrecht, Utrechtthe Netherlands
ProfValentinoBezzerriDepartment of Life Sciences, Health, and Health Professions, Link Campus University, Rome ; Cystic Fibrosis Center, Azienda Ospedaliera Universitaria Integrata, VeronaItaly
ProfAleksandraCatic DjordjevicDepartment of Pharmacy, Faculty of Medicine, University of NisSerbia
DrGiacomoCavalcaClinical Bioinformatics Unit, IRCCS Istituto Giannina Gaslini , Genoa; Alma Mater Studiorum – University of Bologna, BolognaItaly
DrRenatoCerqueiraDepartment of Clinical and Experimental Oncology, Federal University of São Paulo (UNIFESP), Sao PaoloBrazil
MsGabrielaChabrzykDepartment of Pediatrics, Oncology and Hematology, Medical University of Lodz, LodzPoland
ProfJoannaCichyDepartment of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, KrakówPoland
DrCarloDufourUnit of Hematology-IRCCS Istituto Giannina Gaslini, GenoaItaly
ProfAristidisEliopoulosMedical School, National and Kapodistrian University of Athens, AthensGreece
DrFrancescaFioreddaUnit of Hematology-IRCCS Istituto Giannina Gaslini, GenoaItaly
MrKacperGajewskiDepartment of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, KrakowPoland
MsAnna-SophiaHellmuthDepartment of Oncology, Hematology, Clinical Immunology, and Rheumatology, University Hospital Tuebingen, TuebingenGermany
MsAnca ManuelaHristodorCystic Fibrosis Center, Azienda Ospedaliera Universitaria Integrata, VeronaItaly
DrGülKaradumanKaramanoglu Mehmetbey University, Department of Mathematics, Karaman ; The University of Texas at Arlington, Department of Mathematics, Arlington, TXTurkiye /USA
DrChristinaKaramanidouInstitute of Applied Biosciences, Centre for Research & Technology-Hellas, ThessalonikiGreece
DrVassilisKargasCambridge Institute for Medical Research, University of Cambridge, CambridgeUK
DrMaksimKlimiankouDepartment of Hematology, Oncology, Clinical Immunology, and Rheumatology, University Hospital Tübingen, Tübingen; Faculty of Medicine University Tübingen, Gene and RNA Therapy Center (GRTC), Tübingen;Severe Chronic Neutropenia International Registry, SCNIR, HannoverGermany
DrEdwardLaaneHematology-Oncology Clinic, Tartu University, TartuEstonia
ProfIliasLagkouvardosDepartment of Clinical Microbiology, School of Medicine, University of Crete, HeraklionGreece
DrHelenLatsoudisInformation Systems Laboratory (ICS), Institute of Computer Science, Foundation for Research and Technology Hellas (FORTH); Haemopoiesis Research Lab, School of Medicine, University of Crete, HeraklionGreece
MrVolodymyrLotushkoSpecialized Working Group (SWG) Manager, European Hematology Association (EHA)the Netherlands
DrVahagnMakaryanDepartment of Medicine, University of Washington, Seattle, WAUSA
ProfGeorgiosManikisAssociate Professor, Department of Electrical & Computer Engineering, Hellenic Mediterranean University, Heraklion, Crete; Collaborating researcher, Computational Biomedicine Laboratory(CBML), Institute of Computer Sciences(ICS), Foundation for Research and Technology (FORTH), Heraklion, CreteGreece
DrAngelikaMazurDepartment of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, KrakowPoland
ProfHelenPapadakiHaemopoiesis Research Laboratory, University of Crete, Heraklion; Hematology Department,University Hospital of Heraklion, HeraklionGreece
DrPanayiotaPapasavvaDepartment of Molecular Genetics Thalassemia, The Cyprus Institute of Neurology & Genetics, Nicosia; Cyprus School of Molecular Medicine, NicosiaCyprus
DrKonstantiaPavlakiGerman Medical Institute, LemesosCyprus
ProfIordanisPelagiadisPediatric Hematology-Oncology Department, University of Crete, Heraklion; University Hospital of Heraklion, HeraklionGreece
ProfAntonioPieriniHematology and Clinical Immunology Section, Center for Hemato-Oncology Research, Department of Medicine and Surgery, University of Perugia, PerugiaItaly
DrSimoneRivaMRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford,; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, University of Oxford, OxfordUK
ProfAntalRotFaculty of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, LondonUK
DrSamSalekSchool of Life and Medical Sciences, University of Hertfordshire, HatfieldUK
DrChristinaSimoglou KaraliDepartment of Biology, School of Medicine, National and Kapodistrian University of Athens, Athens; Medical Research Council Weatherall Institute of Molecular Medicine (MRC WIMM) and NIHR Biomedical Research Centre Hematology Theme, University of Oxford, OxfordGreece/UK
MrIvanSinkevichDepartment of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków; Doctoral School of Exact and Natural Sciences, Jagiellonian University, KrakowPoland
ProfAnitaSkakicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, BelgradeSerbia
ProfJuliaSkokowaDepartment of Hematology, Oncology, Clinical Immunology, and Rheumatology, University Hospital Tübingen, Tübingen; Faculty of Medicine University Tübingen, Gene and RNA Therapy Center (GRTC), Tübingen;Severe Chronic Neutropenia International Registry, SCNIR, HannoverGermany
DrJoannaSkrzeczynska -MoncznikResearch Scientist, Jagiellonian University, KrakowPoland
DrMichailSpanoudakisDepartment of Haematology, Warrington and Halton Teaching Hospitals NHS Foundation Trust, CheshireUK
DrOrnaSteinberg – ShemerFaculty of Medicine, Tel Aviv University, Tel Aviv; Pediatric Hematology Laboratory, Felsenstein Medical Research Center, Petach TikvaIsrael
DrErwinSwartCytek BioSciencesThe Netherlands
ProfKrzysztofSzadeLaboratory of Stem Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, KrakowPoland
MsKateTheochariVice President Β Rare Diseases Greece -Chairpeson Greek Lysosomal Association, AthensGreece
ProfVictorTomacinschiiDepartment of Hematology, Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinau; Department of Hematology, Public Medical Sanitary Institution (PMSI) Institute of Oncology, ChisinauRepublic of Moldova
ProfIvoTouwDepartment of Hematology, Erasmus Medical Center Cancer Institute, Erasmus University Medical Center, Rotterdamthe Netherlands
DrGrigoriosTsaknakisHaemopoiesis Research Lab, School of Medicine, University of Crete, HeraklionGreece
MrVassilisTzikoulisInformation Systems and Applications Department, Digital Governance Unit, University of Crete, HeraklionGreece
ProfAlanWarrenCambridge Institute for Medical Research, Cambridge Biomedical Campus, Cambridge and Department of Haematology, University of Cambridge School of Clinical Medicine, CambridgeUK
ProfKarlWelteDepartment of Pediatric Hematology, Oncology and Bone Marrow Transplantation, Children’s Hospital, University Hospital Tübingen, Tübingen, and Severe Chronic Neutropenia International Registry, SCNIR, HannoverGermany
DrCorneliaZeidlerSevere Chronic Neutropenia International Registry, SCNIR, Hannover & Department of Hematology, Oncology, Clinical Immunology, and Rheumatology, University Hospital Tübingen, TübingenGermany

*In alphabetical order

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